Bibliography

Scientific publications in peer-reviewed journals

Kapustin Y, Chan E, Sarkar R, Wong F, Vorechovsky I, Winston RM, Tatusova T, Dibb NJ. Cryptic splice sites and split genes. Nucleic Acids Res. 2011 39(14):5837-5844.

Winston RM. Does government regulation inhibit embryonic stem cell research and can it be effective? Cell Stem Cell. 2007 1(1):27-34.

Lavery S, El-Shawarby SA, Moissidou M, Taylor D, Turner C, Lavender B, Trew G, Margara R, Winston R. Live birth following preimplantation genetic screening for trisomy 21. Should aneuploidy screening be offered to all older patients undergoing IVF? Hum Fertil (Camb). 2008 11(1):29-32.

Baker JC and Winston RML. Science and policy making: lessons from the UK Parliament. (submitted to Science)

Carlsson IB, Laitinen MP, Scott JE, Louhio H, Tuuri T, Aaaltonen J, Ritvos O, Winston RM, Hovatta O. Kit ligand and c-Kit are expressed during early human ovarian follicular development and their interaction is required for the survival of follicles in long-term culture. Reproduction. 2006 131(4):641-9.

Jarvis S, Elliott DJ, Morgan D, Winston RML, Readhead C. Molecular markers for the assessment of postnatal male germ cell development in the mouse. Hum Reprod. 2005; 20:108-16.

Sills ES, Winston RML, Palermo GD. Journal of Experimental and Clinical Assisted Reproduction: shaping the future of research and practice in reproductive endocrinology/infertility. J Exp Clin Assist Reprod. 2004;1.

Winston R. Playing god? Nature. 2003 Dec 11; 426:603.

Tachataki M, Winston RM, Taylor DM. Quantitative RT-PCR reveals tuberous sclerosis gene, TSC2, mRNA degradation following cryopreservation in the human preimplantation embryo. Mol Hum Reprod. 2003 9:593-601.

Hardy K, Stark J, Winston RM. Maintenance of the inner cell mass in human blastocysts from fragmented embryos. Biol Reprod. 2003 68:1165-9.

Winston RML and Hardy K. Are we ignoring the potential dangers of in vitro fertilization and related treatments? Nature Cell Biology: 2002 Oct. 4, S14-S19.

Lavery SA, Aurell R, Turner C, Castello C, Veiga A, Barri PN, Winston RM. Preimplantation genetic diagnosis: patients' experiences and attitudes. Hum Reprod. 2002 Sep;17:2464-7.

Spanos S, Rice S, Karagiannis P, Taylor D, Becker DL, Winston RM, Hardy K. Caspase activity and expression of cell death genes during development of human preimplantation embryos. Reproduction. 2002 Sep;124:353-63.

Abou-Sleiman PM, Apessos A, Harper JC, Serhal P, Winston RM, Delhanty JD. First application of preimplantation genetic diagnosis to neurofibromatosis type 2 (NF2). Prenat Diagn. 2002;22:519-24.

George AJ, Gale R, Korn D, Winston R. Research governance at the crossroads. Nature Medicine. 2002;8:99-101.

Makrigiannakis A, Coukos G, Mantani A, Prokopakis P, Trew G, Margara R, Winston R, White J. Expression of Wilms' tumor suppressor gene (WT1) in human endometrium: regulation through decidual differentiation. J Clin Endocrinol Metab. 2001;86:5964-72.

Van den Broecke R, Liu J, Handyside A, Van der Elst JC, Krausz T, Dhont M, Winston RM, Hovatta O. Follicular growth in fresh and cryopreserved human ovarian cortical grafts transplanted to immunodeficient mice. Eur J Obstet Gynecol Reprod Biol. 2001;97:193-201.

Horne AW, White JO, Margara RA, Williams R, Winston RM, Lalani E. MUC 1: a genetic susceptibility to infertility? Lancet. 2001;357(9265):1336-7.

Ravhon A, Lavery S, Aurell R, Trew G, Margara R, Winston R. Clinical experience with recombinant follicle-stimulating hormone (FSH) and urinary FSH: a retrospective case-controlled analysis. Fertil Steril. 2001;75:920-5.

Winston R. Embryonic stem cell research. The case for. Nature Medicine. 2001;7:396-7.

Hardy K, Spanos S, Becker D, Iannelli P, Winston RM, Stark J. From cell death to embryo arrest: mathematical models of human preimplantation embryo development. Proc Natl Acad Sci U S A. 2001;98(4):1655-60.

Taylor DM, Handyside AH, Ray PF, Dibb NJ, Winston RM, Ao A. Quantitative measurement of transcript levels throughout human preimplantation development: analysis of hypoxanthine phosphoribosyl transferase. Mol Hum Reprod. 2001;7:147-54.

Hardy K, Wright CS, Franks S, Winston RM. In vitro maturation of oocytes. Br Med Bull. 2000;56:588-602.

Spanos S, Becker DL, Winston RM, Hardy K. (2000) Anti-apoptotic action of insulin-like growth factor-I during human preimplantation embryo development. Biol Reprod. 63:1413-20.

Ravhon A, Lavery S, Michael S, Donaldson M, Margara R, Trew G, Winston R. Dynamic assays of inhibin B and oestradiol following buserelin acetate administration as predictors of ovarian response in IVF. Hum Reprod. 2000;15:2297-301.

Ravhon A, Lawrie H, Ellenbogen A, Lavery S, Trew G, Winston R. A prospective, randomized controlled trial comparing the efficacy of recombinant follicle-stimulating hormone in three different in vitro fertilization protocols. Fertil Steril. 2000;73:908-12.

Ravhon A, Aurell R, Lawrie H, Margara R, Winston RM. The significance of delayed suppression using buserelin acetate and recombinant follicle-stimulating hormone in a long protocol in vitro fertilization program. Fertil Steril. 2000;73:325-9.

Conn CM, Cozzi J, Harper JC, Winston RML, Delhanty JD (1999) Preimplantation genetic diagnosis for couples at high risk of Down syndrome pregnancy owing to parental translocation or mosaicism. J Med Genet. 36:45-50.

Cozzi J, Conn CM, Harper JC, Winston RML, Rindl M, Farndon PA, Delhanty JD (1999) A trisomic germ cell line and precocious chromatid segregation leads to recurrent trisomy 21 conception. Hum Genet. 104:23-8.

Ray PF, Harper JC, Ao A, Taylor DM, Winston RM, Hughes M, Handyside AH (1999) Successful preimplantation genetic diagnosis for sex-linked Lesch-Nyhan Syndrome using specific diagnosis. Prenat Diagn 19:1237-41.

Devreker F, Van den Bergh M, Biramane J, Winston RML, Englert Y, Hardy K (1999) Effects of taurine on human embryo development in vitro. Hum Reprod 14:2350-6.

Wright CS, Hovatta O, Margara R, Trew G, Winston RM, Franks S, Hardy K (1999) Effects of follicle-stimulating hormone and serum substitution on the in-vitro growth of human ovarian follicles. Hum Reprod. 14:1555-62.

Conn CM, Harper JC, Winston RM, Delhanty JD (1998) Infertile couples with Robertsonian translocations: preimplantation genetic analysis of embryos reveals chaotic cleavage divisions. Hum Genet;102(1):117-123.

Devreker F, Winston RM, Hardy K (1998) Glutamine improves human preimplantation development in vitro. Fertil Steril;69(2):293-299.

Ao A, Wells D, Handyside AH, Winston RM, Delhanty JD (1998) Preimplantation genetic diagnosis of inherited cancer: familial adenomatous polyposis coli. J Assist Reprod Genet;15(3):140-144.

Conaghan J, Hardy K, Leese HJ, Winston RML, Handyside AH (1998) Culture of preimplantation embryos to the blastocyst stage: a comparison of three media. Int J Dev Biol;42:885-93.

Lighten AD, Moore GE, Winston RML, Hardy K (1998) Routine addition of human insulin-like growth factor-1 ligand could benefit clinical in-vitro fertilization culture. Hum Reprod. 13:3144-50.

Ray PF, Ao A, Taylor DM, Winston RML, Handyside AH (1998) Assessment of the reliability of single blastomere analysis for preimplantation diagnosis of the delta F508 deletion causing cystic fibrosis in clinical practice. Prenat Diagn; 18:1402-12.

Delhanty JDA, Harper J, Ao A, Handyside AH, Winston RML (1997) Multicolour FISH detects chromosomal mosaicism in normal preimplantation embryos from fertile patients. Hum Genet 99(6):755-760.

Lighten AD, Hardy K, Winston RML, Moore GE (1997) IGF2 is parentally imprinted in human preimplantation embryos. Nature Genetics 2, 122-123.

Lighten AD, Hardy K, Winston RML, Moore GE (1997) Expression of mRNA for the Insulin-like Growth Factors and their Receptors in Human Preimplantation Embryos. Mol Reprod Dev 47:134-9.

Ray PF, Winston RML, Handyside AH (1997) XIST expression from the maternal X chromosome in human male preimplantation embryos at the blastocyst stage. Hum Molecular Genetics 6: 1323-7.

Taylor DM, Ray PF, Ao A, Winston RM, Handyside AH (1997) Paternal transcripts for glucose-6-phosphate dehydrogenase and adenosine deaminase are first detectable in the human preimplantation embryo at the three- to four-cell stage. Mol Reprod Dev;48(4):442-448.

Soussis I; Harper JC; Kontogianni E; Paraschos T; Packham D; Handyside AH; Winston RML (1996) Pregnancies resulting from embryos biopsied for preimplantation diagnosis of genetic disease: Biochemical and ultrasonic studies in the first trimester of pregnancy. J Assisted Reprod Genetics 13, 254-258.

Ao A; Handyside A; Winston RML (1996) Preimplantation genetic diagnosis of cystic fibrosis (delta F508). Eur J Obstet Gynecol Reprod Biol. 65(1): 7-10.

Kaeda JS, Ray PF, Bingham J, Vulliamy T, Dokal I, Roberts IA, Winston RML, Handyside A (1996) Preimplantation genetic diagnosis of Beta-Thalassaemia Major - Accurate identification of mutations following single cell amplification. Br J Haematol. 93, 198.

Ray PF; Winston RM; Handyside AH (1996) Reduced allele dropout in single-cell analysis for preimplantation genetic diagnosis of cystic fibrosis. J Assist Reprod Genet. 13(2): 104-6.

Ao A; Ray P; Harper J; Lesko J; Paraschos T; Atkinson G; Soussis I; Taylor D; Handyside A; Hughes M; Winston RML (1996) Clinical experience with preimplantation genetic diagnosis of cystic fibrosis (delta F508). Prenat Diagn. 16(2): 137-42.

Soussis I; Harper JC; Handyside AH; Winston RML (1996) Obstetric outcome of pregnancies resulting from embryos biopsied for pre-implantation diagnosis of inherited disease. Br J Obstet Gynaecol. 1996; 103(8): 784-8.

Hardy K, Warner A, Winston RM, Becker DL. (1996) Expression of intercellular junctions during preimplantation development of the human embryo. Molecular Hum Reprod. 2: 621-326.

Nikas G, Ao A, Winston RML, Handyside AH (1996) Compaction and surface polarity of the human embryo in vitro. Biol Reprod. 55, 32-37.

Chia M, Winston RML, Handyside AH (1995) EGF, TGF-alpha and EGFR expression in human preimplantation embryos. Development. 121(2): 299-307.

Ray PF; Conaghan J; Winston RM; Handyside AH (1995) Increased number of cells and metabolic activity in male human preimplantation embryos following in vitro fertilization. J Reprod Fertil. 104: 165-71.

Harper JC; Coonen E; Handyside AH; Winston RML; Hopman AH; Delhanty JD (1995) Mosaicism of autosomes and sex chromosomes in morphologically normal, monospermic preimplantation human embryos. Prenat Diagn 15, 41-9.

Hardy K; Robinson FM; Paraschos T; Wicks R; Franks S; Winston RML (1995) Normal development and metabolic activity of preimplantation embryos in vitro from patients with polycystic ovaries. Hum Reprod 10(8): 2125-35.

Geber S, Handyside AH, Winston RML (1995) Proliferation of blastomeres from biopsied cleavage stage human embryos in vitro: an alternative to blastocyst biopsy for preimplantation diagnosis. Hum Reprod 10(6): 1492-6.

Delhanty JDA, Ao A, Wells D, Handyside AH, Winston RML (1995) Single cell analysis of the APC gene for preimplantation genetic diagnosis of familial adenomatous polyposis coli. Am J Hum Genet. 57, 1614.

Conn CM, Harper JC, Winston RML, Delhanty JDA (1995) Preimplantation diagnosis for trisomy 13, trisomy 14, trisomy 18, and trisomy 21 in translocation carriers using multicolor fluorescent in situ hybridization. Am J Hum Genet. 57, 1611.

Harper JC; Dawson K; Delhanty JA; Winston RML (1995) The use of fluorescent in-situ hybridization (FISH) for the analysis of in-vitro fertilization embryos: A diagnostic tool for the infertile couple. Hum Reprod 10 (12) 3255-3258.

Delhanty JD, Handyside AH, Winston RML, Hughes M (1994) Sex determination of preimplantation embryos. Lancet 343, 549.

Harper JC, Coonen E, Ramaekers FCS, Delhanty JDA, Handyside AH, Winston RML, Hopman AHN (1994) Identification of the sex of human preimplantation embryos in two hours using an improved spreading method and fluorescent in-situ hybridization (FISH) using directly labelled probes. Hum Reprod 9, 721-4.

Delhanty JD; Handyside AH; Winston RML (1994) Preimplantation diagnosis. Lancet. 343(8912): 1569-70.

Griffin DK, Handyside AH, Harper JC, Wilton LJ, Atkinson GA, Soussis J, Ao A, Delhanty JDA, Winston RML (1994) Clinical experience with preimplantation diagnosis of sex by fluorescent in situ hybridization. J Ass Rep Gen, 11, 3, 141-51.

Harper JC; Robinson F; Duffy S; Griffin DK; Handyside AH; Delhanty JD; Winston RM (1994) Detection of fertilization in embryos with accelerated cleavage by fluorescent in-situ hybridization (FISH). Hum Reprod 9, 1733-7.

Winston RML (1994) Limitations to human germ-line gene therapy. Politics and the Life Sciences, 13, 237-9.

Ao A, Erickson RP, Winston RML, Handyside AH (1994) Transcription of paternal Y-linked genes in the human zygote as early as the pronucleate stage. Zygote. 2(4): 281-7.

Schrurs BM, Winston RML, Handyside AH (1993) Preimplantation diagnosis of aneuploidy using fluorescent in-situ hybridization: evaluation using a chromosome 18-specific probe. Hum Reprod 8, 296-301.

Tarin JJ, Conaghan J, Winston RML, Handyside AH (1993) Human embryo biopsy on the 2nd day after insemination for preimplantation diagnosis: removal of a quarter of the embryo retards cleavage. Fertil Steril 58, 970-6.

Griffin DK, Wilton LJ, Handyside AH, Atkinson GH, Winston RML, Delhanty JD (1993) Diagnosis of sex in preimplantation embryos by fluorescent in situ hybridisation. BMJ 306, 1382.

Conaghan J, Hardy K, Handyside AH, Winston RML, Leese HJ (1993) Selection criteria for human embryo transfer: a comparison of pyruvate uptake and morphology. J Assist Reprod Genet 10, 21-30.

Winston RML, Handyside AH (1993) New Challenges in human in vitro fertilization. Science 260, 932-6.

Conaghan J, Handyside AH, Winston RML, Leese HJ (1993) Effects of pyruvate and glucose on the development of human preimplantation embryos in vitro. J Reprod Fertil 99, 87-95.

Martin KL, Hardy K, Winston RML, Leese HJ (1993) Activity of enzymes of energy metabolism in single human preimplantation embryos. J Reprod Fertil 99, 259-66.

Hardy K, Winston RML, Handyside AH (1993) Binucleate blastomeres in preimplantation human embryos in vitro: failure of cytokinesis during early cleavage. J Reprod Fertil 98, 549-58.

Delhanty JD, Griffin DK, Handyside AH, Harper J, Atkinson GH, Pieters MH, Winston RML (1993) Detection of aneuploidy and chromosomal abnormality in embryos. Hum Reprod 8, 1696-700.

Griffin DK, Wilton LJ, Handyside AH, Winston RML, Delhanty JDA (1992) Dual fluorescent in situ hybridisation for simultaneous detection of X-chromosome-specific and Y-chromosome-specific probes for the sexing of human preimplantation embryonic nuclei. Hum Genet. 89, 18-24.

Conaghan J, Hardy K, Winston RML, Leese HJ (1992) Pyruvate uptake in relation to pregnancy outcome after human IVF. J. Reprod Fertil, 27, 39.

Handyside AH; Lesko JG; Tarin JJ; Winston RM; Hughes MR (1992) Birth of a normal girl after in vitro fertilization and preimplantation diagnostic testing for cystic fibrosis. N Engl J Med, 327 (13) 905-9.

Conaghan J, Handyside AH, Winston RML, Leese HJ. (1992) Glucose inhibits cleavage of human preimplantation embryos in vitro. J Reprod Fertil, 10, 4.

Geber S, Winston RML, Handyside AH (1992) Blastomeres isolated by cleavage stage biopsy of human embryos form trophectoderm vesicles in vitro. J Reprod Fertil. 10, 51.

Handyside AH, Harper J, Winston RML (1992) Preliminary evaluation of the use of in vitro fertilisation for preimplantation diagnosis of inherited disease. J Reprod Fertil. 10, 53.

Winston RML, Handyside AH, Hardy K (1992) BABI in dispute. Nat Genet, 1, 320.

Leese HJ; Humpherson PG; Hardy K; Hooper MA; Winston RM; Handyside AH (1991) Profiles of hypoxanthine guanine phosphoribosyl transferase and adenine phosphoribosyl transferase activities measured in single preimplantation human embryos by high-performance liquid chromatography. J Reprod Fertil, 91 (1)197-202.

Gott AL, Hardy KL, Winston RML, Leese HJ (1990) Non-invasive measurement of pyruvate and glucose uptake and lactate production by single human preimplantation embryos. Human Reprod. 5, 104.

Soussis I, Jeer H, Packham C, Margara RA, Handyside AH, Winston RML (1991) Ultrasonic and biochemical parameters of early pregnancies following transfer of biopsied human embryos for X-linked genetic disorders. Hum Reprod 6, 138.

Griffin DK, Handyside AH, Penketh RJA, Winston RML, Delhanty JDA (1991) Fluorescent in situ hybridisation to interphase nuclei of human preimplantation embryos with X and Y chromosome specific probes. Human Reprod. 6, 101-105.

Hardy K, Winston RML, Handyside AH (1991) Nuclear abnormalities and developmental arrest in human preimplantation embryos in vitro. Hum Reprod 6, 152.

Griffin DK, Delhanty JDA, Handyside AH, Winston RML (1991) Preimplantation diagnosis for sex-linked disorders using fluorescent in situ hybridisation. Clin. Genetics.

Conaghan J, Martin K, Hardy K, Winston NJ, Dawson KJ, Winston RML (1991) Prospects for pre-transfer assessment of human embryo viability following in vitro fertilization. Hum Reprod 6, 232.

Winston RML, Soussis J, Dawson K, Handyside AH (1991) The relevance of preimplantation diagnosis for genetic defects. Hum Reprod 6, 281.

Hardy KL, Leese HJ, Martin KL, Handyside AH, Winston RML (1990) Human preimplantation development after biopsy at the 8-cell stage. J. Reprod. Fertil. 49, 87.

Hardy KL, Winston RML, Handyside AH (1990) Binucleate cells in human preimplantation embryos in vitro: failure of cytokinesis during early cleavage. J Reprod Fertil 24, 38.

Handyside AH, Kontogianni EH, Hardy K, Winston RML (1990) Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification. Nature, 344, 768.

Gott AL, Hardy K, Winston RML, Leese HJ (1990) The nutrition and environment of the early human embryo. Proc. Nutr. Soc. 49 (1) 2A.

Hardy KL, Leese HJ, Martin KL, Winston RML, Handyside AH (1990) Human preimplantation development in vitro is not adversely affected by biopsy at the 8-cell stage. Human Reprod. 5, 708-14.

Handyside AH, Hardy K, Penketh RJA, Hooper MAK, Humpherson P, Leese HJ, Winston RML (1989) Preimplantation diagnosis of Lesch-Nyhan Syndrome. Hum. Reprod. 3 (suppl), 44.

Hardy K, Hooper MAK, Handyside AH, Winston RML, Leese HJ. (1989) Non-invasive measurement of glucose and pyruvic acid uptake by individual human pre-embryos. Hum. Reprod. 4, 188-91.

Handyside AH, Pattinson JK, Penketh RJA, Delhanty JDA, Tuddenham EDG, Winston RML (1989) Lancet, ii, 347-9.

Penketh RJA, Delhanty JDA, Finkelstone EM, Handyside AH, Malcolm S, Winston RML (1989) Rapid sexing of human embryos by non radioactive in situ hybridisation. Proc. Eur Soc Hum. Rep. 1, 132.

Coutelle C, Williams C, Handyside A, Hardy K, Winston R, Williamson R (1989) Genetic analysis of DNA from single human oocytes: a model for preimplantation diagnosis. Brit Med. J., 299, 22-5.

Winston RML, Handyside AH, Penketh R. (1989) Embryo biopsy. Lancet, i, 1323.

Penketh RJA, Delhanty JDA, van den Berghe JA, Finkelstone EM, Handyside AH, Malcolm S, Winston RML. (1989) Rapid sexing of human embryos by non-radioactive in situ hybridisation: potential for preimplantation diagnosis of X-linked disorders. Prenatal Diagnosis, 9, 489-500.

Polson DW, Mason HD, Kiddy DS, Winston RML, Margara RA, Franks S. (1989) Low dose FSH in the treatment of polycystic ovarian syndrome. A comparison of pulsatile subcutaneous with daily intra-muscular therapy.

Hardy KL, Handyside AH, Winston RML (1989) The human blastocyst: Cell number, death and allocation during late preimplantation development in vitro. Development, 107, 597.

In vitro fertilisation

Winston RML. Test tube babies: The ethical dimension. Nursing Times, 80, 29, 20-21, 1984.

Winston RML, Margara RA and Hillier SG. Tubal microsurgery and in vitro fertilization. Clin. Reprod. Fertil. 3, 153-4, 1985.

Dawson KJ, Hillier SG, Wickings EJ, Margara RA, Winston RML. Embryo development and quality control in in vitro fertilization. In In Vitro Fertilization and Donor Insemination, RCOG, London, 1985. 125-137.

Winston RML, Margara RA, Hanna L, Hillier SG. Preparation of the pelvis for in vitro fertilization. In In Vitro Fertilization and Donor Insemination, RCOG London, 1985. 173-182.

Winston RML and Hillier SG. IVF versus nature. Lancet i, 284, 1985.

Hillier SG, Winston RML, Margara RA, Afnan MA. Superovulation strategy before in vitro fertilization treatment cycles. Clin. Obstet. Gynaec. 12, 687-723, 1985.

Winston RML and Hillier SG. The interface between tubal surgery and in vitro fertilization. Clin. Obstet. Gynaecol. 1986.

Golan A, Dargenio R, Winston RML. Effect of treatment of experimentally produced endometrial peritoneal implants. Fertil. Steril., 46, 954-8. 1986.

Winston RML and Margara RA. Effectiveness of treatment for infertility. Br. Med. J., 295, 608, 1987.

Winston RML, Margara RA. Clinical algorithms: infertility. Br. Med. J. 294, 1230, 1987.

Otubu JA, Winston RML. Spontaneous contractile pattern of isolated circular and longitudinal muscle layers from ampullae of normal and damaged fallopian tubes. Afr. J. Med. med Sci. 16(1), 33-7, 1987.

Winston RML. Why a ban on embryo research would be a tragedy. Brit Med J. 295, 1501-2, 1987.

Rutherford AR, Subak-Sharpe RJ, Dawson KJ, Margara RA, Franks S, Winston RML. Improvement of in vitro fertilisation after treatment with buserelin, an agonist of luteinising hormone releasing hormone. Brit. Med. J. 296, 1765-8. 1988.

Dawson KJ, Rutherford AJ, Winston NJ, Subak-Sharpe R, Winston RML. (1988) Human blastocyst transfer; is it a feasible proposition? Hum. Reprod., 3 44-5.

Conaghan J, Dimitry E, Mills M, Margara RA, Winston RML (1989) Delayed hCG administration for in vitro fertilization. Lancet, ii, 1323-1324.

Golombok S, Bhanji F, Rutherford AR, Winston RML (1990) Psychological development of children of the new reproductive technologies. J. Inf. Reprod. Psychol. 27, 203.

Rizk B, Dimitry ES, Morcos S, Edwards RG, Brinsden P, Winston RML (1990) A multicentre study on combined intrauterine and extrauterine pregnancy after IVF. Hum Reprod 5, 113-4.

Winston RML (1991) In vitro fertilization or tubal surgery? Lancet ii, 337, 1096.

Oskarsson T, Dimitry ES, Mills MS, Hunt J, Winston RML (1991) Attitudes towards gamete donation among couples undergoing in vitro fertilization. Br J Obstet Gynaecol 98, 351-6.

Dawson KJ, Rutherford AJ, Margara RA, Winston RML (1991) Reducing triplet pregnancies following in-vitro fertilisation. Lancet 337 (8756) 1543-4.

Packham C, Dawson KJ, Margara RA, Winston RML (1991) Levels of hCG in early pregnancy following IVF and embryo transfer. Hum Reprod 6, 413-6.

Dimitry ES, Oskarsson T, Conaghan J, Margara RA, Winston RML (1991) Beneficial effect of a 24 hr delay in hCG administration during in vitro fertilization treatment cycles. Hum Reprod 6, 922-4.

Winston RML, Dawson KJ, Margara RA, Duffy S (1992) Age and IVF outcome. J Reprod Fertil. 10, 44.

Winston RML (1992) Tubal surgery or in vitro fertilization? J Assist Reprod Genet 9, 309-11.

Baker G, Brinsden P, Jouannet P, Loumaye E, Van Steirteghem A, Winston R (1993) Treatment of severe male infertility with pure follicle-stimulating hormone (FSH). Hum Reprod 8, 500-1.

Atkinson G, Apperley J, Dawson K, Goldman J, Winston RML (1994) Successful pregnancy after allogeneic bone marrow transplantation for chronic myeloid leukaemia. Lancet 344, 199.

Dawson KJ, Conaghan J, Ostera GR, Winston RML, Hardy K (1995) Delaying transfer to the third day post-insemination, to select non-arrested embryos, increases development to the fetal heart stage. Hum Reprod 10, 177-82.

Hovatta O, Silye R, Krausz T, Abir R, Margara R, Trew G, Lass A, Winston RM (1996) Cryopreservation of human ovarian tissue using dimethylsulphoxide and propanediol-sucrose as cryoprotectants. Hum Reprod. 11: 1268-72.

Winston RML (1996) Widows fight for husband's sperm - Intervention by BMA Ethics Committee was ill-judged. Br Med J: 313, 1477.

Lass A, Croucher C, Duffy S, Dawson K, Margara R, Winston RML (1998) One thousand initiated cycles of in vitro fertilization in women aged 40 years and over. Fertil Steril 70, 1030-4.

Winston RML (1998) League tables of in vitro fertilisation clinics misinform patients. Brit Med J; 317:1593-4.

Lavery SA, Aurell R, Turner C, Taylor DM, Winston RML (2000) An analysis of the demand for and cost of preimplantation genetic diagnosis in the United Kingdom. Prenat Diagn. 19:1205-8.

Physiology and microsurgery of the Fallopian tube

Winston RML and McClure Browne JC. Pregnancy following autograft transplantation of the fallopian tube and ovary in the rabbit. Lancet 11:494, 1974.

Winston RML (1975) Tube transplants. Brit. Med. J. I: 230, 1975.

Winston RML (1975) Microsurgical reanastomosis of the rabbit Fallopian tube and its functional and pathological sequelae. Brit. J. Obstet. Gynaecol. 82:513.

Winston RML (1977) Microsurgical tubo-cornual anastomosis for reversal of sterilization. Lancet I:284.

Winston RML, Frantzen C, Oberti C (1977) Oviduct function following resection of the ampullary-isthmic junction. Fertil. Steril. 28:284.

Winston RML (1977) Why 103 women requested reversal of sterilization. Brit Med J. 2:305.

Winston RML. Reversal of sterilization: Microsurgery of the Fallopian Tube. In Reversibility of Sterilization, Harper and Row, New York. 184-194, 1978.

Winston RML. The future of microsurgery in infertility. Clin Obstet Gynaecol 5(3):607, 1978.

Winston RML. Microsurgery of the Fallopian tube (1980) From fantasy to reality. Fertil. Steril. 34: 521.

Winston RML (1980) Atraumatic conservative pelvic surgery. In Microsurgery in Female Infertility, Academic Press, London, 121-125.

Winston RML and Margara RA. Technique for the improvement of microsurgical tubal anastomosis. In Microsurgery in Female Infertility, Academic Press, London, 25-34, 1980.

Winston RML: Is microsurgery necessary for salpingostomy? Aust NZ J Obstet Gynaecol. 21, 143-152, 1981.

Winston RML. Progress in tubal surgery. Clin. Obstet. Gynaecol. 8, 653-679, 1981.

Winston RML. Microsurgery for tubal and ovarian disease. Ann Chir. Gynaecol. 71, 97-102, 1982.

Vasquez G, Winston RML, Brosens IA. Tubal mucosa and ectopic pregnancy. Brit. J. Obstet. Gynaecol. 90, 468-474, 1983.

Winston RML and Margara RA. Conservative surgical management of ectopic pregnancy. J. Obstet. Gynaecol., 5, suppl 1, 1-4, 1984.

Winston RML, Margara RA (1991) Microsurgical salpingostomy is not an obsolete procedure. Br J Obstet Gynaecol 98, 637-642.

Brewis IA, Winston RML, Leese HJ (1992) Energy metabolism of the human fallopian tube. J Reprod Fert. 95, 257-62.

Dimitry ES, Soussis I, Oskarsson T, Margara RA, Winston RML (1992) The use of transvaginal ultrasound in the diagnosis of ectopic pregnancy. J Obstet Gynecol 12, 258-61.

The ovary and ovulation

Balmeceda JP, Eddy CA, Winston RML, Asch RH. Perfusion of the Rhesus monkey ovary. Fertil. Steril. 37, 309-310, 1982.

Winston RML, Margara RA, Hillier SG. Technique and results of ovariolysis in preparation for in vitro fertilization. Europ. J. Obstet Gynaec., 18, 381-90, 1984.

Hillier SG, Parsons JH, Margara RA, Winston RML. Serum estradiol and preovulatory follicular development before in vitro fertilization. J. Endocr. 101, 113-118, 1984.

Hillier SG, Wickings EJ, Afnan M, Margara RA, Winston RML. Granulosa cell steroidogenesis before in-vitro fertilization. Biology of Reproduction. 31, 679-686, 1984.

Afnan M, Hillier SG, Winston RML, Franks S. Pulsatile gonadotrophin treatment for in-vitro fertilization. Lancet, i, 1239, 1984.

Harlow CR, Winston RML, Margara RA, Hillier SG. Gonadotrophic control of human granulosa cell glycolysis. Hum. Reprod., 2, 649-653, 1987.

Franks S, Mason HD, Polson DW, Winston RML, Margara RA, Reed MJ. The mechanism and management of ovulatory failure in women with Polycystic Ovarian Syndrome. Human Reproduction, 3 (4), 531-4, 1988.

Fisch B, Winston RML, Hillier SG. Isolation and characterisation in vitro of steroidogenic cells from the human corpus luteum. J. Endocrinol. 1989; 122, 303-11.

Mason HD, Margara R, Winston RML, Seppala M, Koistinen R, Franks S (1993) Insulin-like growth factor-I inhibits production of IGF-binding protein-1 while stimulating estradiol secretion in granulosa cells from normal and polycystic ovaries. J Clin Endocrinol Metab 76, 1275-9.

Harlow CR, Jenkins JM, Winston RML (1997) Increased follicular fluid total and free cortisol levels during the luteinizing hormone surge. Fertil Steril 68(1):48-53.

General and miscellaneous

Naish FP, Clark A, Winston RML, Peters DK (1973) Serum and urine fibrinogen derivatives in normal pregnancy and pre-eclampsia. Obstet. Gynecol. 42:861.

Winston RML (1974) The relation between size and pathogenicity of Trichomonas vaginalis. J. Obstet. Brit. Comm. 81:399.

Wigglesworth JS, Winston RML, Bartlett K (1977) Influence of the central nervous system in fetal lung development. Arch. Dis. Childhood 52:965.

Golan A, Dargenio R, Winston RML (1984) Experimental endometriosis: A microsurgical animal model in rats. Isr. J. Med. Sci. 20: 1094-6.

Margara RA, Winston RML (1984) Myomectomy. J. Obstet. Gynaecol., 5,1, 33-6.

Margara RA, Winston RML (1988) The results of treatment of intrauterine synechiae. J. Obstet. Gynaecol. 74-86.

Brosens JJ, de Souza NM, Barker FG, Paraschos T, Winston RML (1995) Endovaginal ultrasonography in the diagnosis of adenomyosis uteri. Br J Obstet Gynaecol. 102(6): 471-4.

de Souza NM, Brosens JJ, Schwieso JE, Paraschos T, Winston RML (1995) The potential value of magnetic resonance imaging in infertility. Clin Radiol 50, 75-9.

Selected review articles and editorials

Winston RML (1989) The management of the infertile patient in general practice. General Practitioner, 2, 1-8.

Winston RML (1991) Allocation of resources for infertility treatments. Bailliere's Clin Obstet Gynaecol 5, 551-73.

Winston RML (1992) The selection of IVF or microsurgery. Editorial. J IVF Gen, 9, 309-311.

Winston RML (1994) Treating menopausal infertile women. Brit J Hosp Med 47, 88.

Winston RML (1997) The promise of cloning for human medicine. Br Med J 314, 913-4.

Books and chapters in books

Winston RML. Obstetric and gynaecological section. In Modern Surgery for Nurses, Heinemann 9th edition, London, 1974.

Brosens I and Winston RML (Editors). Reversibility of Female Sterilization. Academic Press, London, 1978.

Chamberlain GVP and Winston RML. Tubal Infertility. Blackwells, London, 1981.

Winston RML and Darling M. Infertility for Undergraduates and Postgraduates. Pergamon Press, 1986.

Winston RML. Infertility. Overview of recent therapeutic developments. Martin Dunitz, London, 1993.

Winston RML, Handyside AH (1994) Clinical results of preimplantation genetic diagnosis. In Serono Symposia series.

Professional teaching films and videotapes

The use of the microscope for salpingostomy. 16mm film. Prize at AFS, Miami, 1977.

Tubocornual anastomosis for inflammatory disease. 16mm film. First shown Madrid, 1978.

Microsurgery for Sterilization Reversal. 16mm film. First shown Seoul, Korea, 1979.

Transplantation of the Human Fallopian Tube. 16mm film. Grenoble, 1981.

Salpingostomy simplified. 16mm film. Bombay, 1983.

Tubocornual Anastomosis. Teaching videotape sponsored by Winthrop Laboratories, 1985.

Preparation of the Pelvis for IVF. Teaching videotape sponsored by Winthrop Laboratories, 1985.

Endometriosis. Teaching videotape, Winthrop-Sterling, 1987.

Artificial insemination. Teaching videotape, Organon Laboratories, 1992.

Laparoscopic surgery. Video-programme made for Royal College of Obstetricians & Gynaecologists, 1992.